Good comment, CT. I took out the “modern parlance” bit. (As I recall, that part of the comment wasn’t mine…)

Good annotation until the ‘translation’ into modern parlance. There is no cynical dismissal of life in anything Claudius says in this scene. In fact, it’s the exact opposite. Claudius plays as if he is the exemplar of life’s positive qualities – which exist in intimate and unavoidable relationship with life’s sorrow.

The verse “Soon we’ll be free of blot and mixture” refers to the letters that Thomas Jefferson wrote to James Monroe. That particular passage reads as follows “ when our rapid multiplication will expand itself beyond those limits, & cover the whole northern, if not the southern continent, with a people speaking the same language, governed in similar forms, & by similar laws; nor can we contemplate with satisfaction either blot or mixture on that surface. ”

There are some people in Israel, the most right-wing hard-liners, who wish to see all Arabs “transferred” out of Israel in a kind of “peaceful” ethnic cleansing. That is to say, displaced out of Israel into some neighbouring Arab state, as happened during the founding of Israel in May 1948 (an event known as the ‘Nakba’ to many Arabs). Avigdor Lieberman, the current (as of March 2017) defense minister, is perhaps the most high-profile spokesperson for this faction. This is viewed by some in Israel as a necessity for Israel to maintain its status as both a democracy and an ethno-state (that is, Israel as a Jewish state, not just a state), since if Arabs are given the vote and are allowed to remain in the country, they will not elect leaders who will preserve the state’s “Jewish character.” This is known as Israel’s “demographic problem”, for which this kind of “peaceful” ethnic cleansing is one (extremist) solution.

There is a contrast in the way that the characters are doubting. Banquo is doubting the witches and is distrustful of their nature and whether the prophecy will actually come true whereas Lady Macbeth is doubtful of Macbeth and whether he will be able to actually fulfil the prophecy that the witches have laid out for him.
Highlights the nature of the two characters, and their relationships with Macbeth

Lady Macbeth already has doubts about her husband, and if he will be capable of making the prophecy come true – foreshadows Macbeth being coerced into the decision of killing Duncan

You could also say that this suggest Lady Macbeth as already considering the murder of Duncan as she says he is ‘too full o’ human kindness', meaning he is not able to do a certain task or deed, which would be the murder of Duncan.

Also could the metaphor could also be for the fact that she physically lacks milk in her breasts, as she lost her baby. This shows she emotionally lacks “milk” as is less compassionate.

‘Milk’ is associated with purity, which could indicate that lady macbeth feels macbeth is too pure and innocent to commit such sinful acts. It is alligning him with femininity, which suggests that he stereotypically, like a woman, takes on a nurturing role. Also, note that milk is a symbolism of innocence, and this is seen through the colour and how it’s unaltered. This could inidicate that the ambition lady macbeth has for her husband will ultimately end up being his tragic flaw.

She may be insulting Macbeth by saying that his personality is feminine

It’s amazing that she thinks a virtue (compassion), for which she probably has been drawn to her husband, for which she probably respects her husband, is Macbeth’s greatest weakness in his quest for greatness. Compassion is a good thing… she thinks her husband is good. She also believes that neither ambition nor goodness (both Macbeth’s virtues) serve as pathways to social/political ascendency. (much like today) She believes in Macbeth’s capacity to be a great leader. But she knows that every promotion Macbeth receives, he would want to earn; that he would not cheat (he is honest and honorable)… yet, isn’t so upstanding and pure in his desire to be honorable (like Banquo) that if the King position fell upon him, he would not accept it (‘cause he wants it). She believes that the King-ship is only acquired when it is seized, … it doesn’t just fall upon you because you deserve it. And “the nearest way” – killing Duncan and creating a vacancy – is something Macbeth is afraid to do (perhaps because of his loyalty to the crown…again a good virtue), but Macbeth’s loyalty to the crown is not synonymous with love of Duncan (his own cousin and Lord). If Duncan died, she thinks, Macbeth wouldn’t wish he were alive again…which speaks volumes about their relationship with Duncan. She wants Macbeth to quickly return from the battlefield, now that the war is over, to talk to Macbeth about the prophecy, so that she can influence his perspective and desires, and encourage him to seize the moment to snatch the crown now that he has the support of the other Thanes, now that he is looked up to by so many for his performance on the battlefield against Norway.

Milk represent purity . This shows that Macbeth is too kind and that is what lady Macbeth think that it is Macbeth’s weakness.

Lady Macbeth is more comfortable with murder.